3D-OSEM versus FORE + OSEM: Optimal Reconstruction Algorithm for FDG PET with a Short Acquisition Time

Abstract Objective In this study, we investigated the optimal reconstruction algorithm in fluorodeoxyglucose (FDG) positron emission tomography (PET) with a short acquisition time. Materials and Methods phantom six spheres filled FDG solution (sphere size: 6.23–37 mm; radioactivity ratio of to background = 8:1) placed National Electrical Manufacturers Association were evaluated. Image time was 15 180 seconds, obtained image data reconstructed using each Fourier rebinning (FORE) + ordered subsets expectation-maximization (OSEM) 3D-OSEM algorithms. clinical mid-abdominal images 19 patients evaluated regions interest on areas low, intermediate, high radioactivity. All visually, quantitatively maximum standardized uptake value (SUV) coefficient variation (CV). Results FORE OSEM had large CVs (poor quality) but comparatively constant SUVs. showed (good significantly low The results visual evaluation well correlated those quantitative evaluation. Small obscured time, quality not greatly deteriorated. studies yielded similar results. Conclusion PET by poorer than 3D-OSEM. However, clearer more useful light detection lesions.